ZFIN Image: Rolland et al., 2022, Figure 6

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Figure 6

scRNA-seq analysis of control and MMP14 inhibitor-treated regenerating hearts. (A and B) UMAP clusters of the different populations of cells in control (A) and MMP14 inhibitor-treated (B) zebrafish hearts at 3 dpa. (C) The number of genes per cell type, which shows significantly differential expression between the control and MMP14 inhibitor-treated conditions (P < 0.1). (D) Violin plot compares the expression of mmp14b in MC1, MC2a, MC2b, and MC3 (*P < 0.1, **P < 0.05). (E) UMAP plots depict the relative expression of hbegfb in the different macrophage sub-clusters in control and MMP14 inhibitor-treated conditions (***P < 0.01).

Acknowledgments

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