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Figure 5
Alterations of different organs in npc1 −/− and wild type larvae of 3 wpf. (A) Intestine and liver. In npc1 −/− vacuolation in some enterocytes (intestine: black arrows) and hepatocytes (liver: red arrows) can be observed. (B) Gray matter. In npc1 −/− vacuolation in the brain gray matter is indicated with red arrows. (C) Renal tubules. In npc1 −/− cytoplasmic vacuolation of renal tubule epithelium is observed, some of the vacuoles are marked with black arrows.
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Full text @ Front. Mol. Neurosci.