ZFIN Image: Falat et al., 2022, Fig. 3

Image

Figure Caption

Fig. 3 lama1, lamb1a, and lamc1 are all required for proper MHBC cell length. (A?D) Representative confocal images of memGFP injected embryos imaged at 24 ss, WT (A), and lama1 (B), lamb1a (C), lamc1 (D) mutants. (E?F) Quantification of cell length measurements at the MHBC and posterior region. Boxplots indicate the 25th and 75th percentiles and the median. At least three independent experiments are represented. n ?= ?19 embryos for WT, 9 embryos for lama1 mutants, 6 embryos for lamb1a mutants, and 7 for lamc1 mutants. Significance values ???P ?< ?0.005. Solid yellow lines are representative of cells measured at the MHBC. White dotted lines are representative of cells measured 40 ??m posterior to the MHBC toward the hindbrain. White arrowhead indicates MHBC. M, midbrain; H, hindbrain. Scale bars 20 ??m.

Acknowledgments

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Reprinted from Developmental Biology, 492, Falat, E.J., Voit, G.C., Gutzman, J.H., Laminin-111 mutant studies reveal a hierarchy within laminin-111 genes in their requirement for basal epithelial tissue folding, 172-186, Copyright (2022) with permission from Elsevier. Full text @ Dev. Biol.