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Fig. 2
Fig. 2. Silica crystals promotes macrophage recruitment and monocytosis in zebrafish larvae. SiO2 crystals or PBS were injected in the hindbrain ventricle (HBV, dash line) of 2 dpf Tg(mfap4:mCherry). Macrophage recruitment (A, B) and number in the whole body (C, D) and the head (E) were analyzed by fluorescence microscopy from 1 to 48 hpi (A, B) or 24 hpi (C-E). Each dot represents one individual and the mean ± S.E.M. for each group is also shown. P values were calculated using one-way ANOVA and Tukey multiple range test. ns, not significant, ***p ≤ 0.001. Bars: 100 μm (A), 500 μm (C).
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