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Fig. 3.
Long bone overgrowth is non-progressive. Overgrown long bones in akt1E18K-GFP mosaic larvae elongate at the same rate as bones in control larvae. (A) Ratio of the length of endochondral bone hypural 1 to SL over time (SL 5.8-10 mm) in akt1E18K-GFP (n=7) and GFP (n=5) mosaic larvae. (B) Analyzed bone (GFP+ hypural 1 of the caudal fin). (C) Representative in vivo confocal image of the caudal fin of an analyzed GFP (green) mosaic larva. Tg(sox10:DsRed) marks chondrocytes (magenta). Arrows mark hypural 1. SL, standard length in mm. Scale bar: 50 ?m.
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Full text @ Dis. Model. Mech.