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Fig. 9
HI-NESS can be used to visualise chromosome dynamics during the cell cycle (wide field microscopy, single Z-plane). A time-lapse of a dividing HeLa cell (Movie S8) shows that HI-NESS remains bound to the chromosome during mitosis. From left to right: Phase contrast image, Lck-mTurquoise2 (membrane label), mScarlet-I-HI-NESS (DNA label).
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Full text @ Nucleic Acids Res.