ZFIN Image: Hu et al., 2021, Fig. 2

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Figure Caption

Fig. 2

irf7 knockdown zebrafish embryos exhibit severe defects in hair cell (HC) development. (a) Phenotypes of control and irf7‐specific morpholino‐injected Tg(Brn3c:GFP) zebrafish larvae at 72 hpf. (b) Fluorescent imaging of green fluorescent protein (GFP)‐labeled HCs indicates the HC clusters on the lateral line of zebrafish larvae at 72 hpf. (c) Quantification of the number of HC clusters in control and irf7‐specific morpholino‐injected Tg(Brn3c:GFP) zebrafish embryos at 72 hpf. (d) Comparison of the phenotypes of crista HCs (blue dotted circles) in control, irf7‐specific morpholino‐injected and irf7‐specific morpholino & mRNA‐coinjected zebrafish embryos. (e) Quantification of the number of crista HCs in control, irf7‐specific morpholino‐injected and irf7‐specific morpholino & mRNA‐coinjected zebrafish embryos. Error bars indicate standard deviation. ***, P < 0.001

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Acknowledgments

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