ZFIN Image: Qi et al., 2023, FIGURE 4

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Figure Caption

FIGURE 4

Beneficial effects of anti-acrolein (ACR), but not hypoglycemic treatment on motor neuron development in ACR treated embryos. (A) Representative confocal images of motor neurons at 24 and 48 hpf upon different treatment. White scale bar: 20 μm. (B,C) Quantification of average length of motor nerves showed significant decrease of axonal length in embryos upon ACR treatment can be well-reversed by L-carnosine (anti-ACR treatment) but not PK11195 (hypoglycemic treatment) at 24 and 48 hpf. n = 5–9. For statistical analysis one-way ANOVA followed by Tukey’s multiple comparisons test was applied. ***p < 0.001, ****p < 0.0001. ns, not significant; hpf, hour post fertilization.

Acknowledgments

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