ZFIN Image: Sabharwal et al., 2022, Figure 5

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Figure Caption

Figure 5—figure supplement 1. lrpprc^{GBT0235/GBT0235} and Tg(fabp10:Cre)lrpprc^{GBT0235/GBT0235} mutants display decreased birefringence at 4 dpf.

Graphs displaying the birefringence area of the region of interest (ROI), mean gray value, and integrated density between lrpprc^+/+, lrpprc^{GBT0235/GBT0235,} and Tg(fabp10:Cre)lrpprc^{GBT0235/GBT0235} mutants at 4 dpf. lrpprc^{GBT0235/GBT0235} mutants display a decrease in mean gray value (p-value = 0.0003) and integrated density (p-value = 0.0002) as compared to wild type, whereas no significant difference in the birefringence area is observed (p-value = 0.1280). Tg(fabp10:Cre)lrpprc^{GBT0235/GBT0235} mutants do not display significant difference in the birefringence area (p-value = 0.1254), mean gray value (p-value = 0.7623) and integrated density (p-value = 0.3622) as compared to lrpprc^{GBT0235/GBT0235} mutants. Each individual data point represents a single animal (For lrpprc^+/+; N=28, lrpprc^{GBT0235/GBT0235}; N=13 and Tg(fabp10:Cre)lrpprc^{GBT0235/GBT0235}; N=13). p-Values were determined using the Mann-Whitney test. (Figure 5—source data 1).

Acknowledgments

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