ZFIN Image: Barrett et al., 2022, FIGURE 7

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Figure Caption

FIGURE 7

Time-course of restoration of SV2 + plexiform layers following extensive lesion. Tissues were processed for indirect immunofluorescence and imaging after ERG recordings. (A) Control retina showing SV2 staining within the outer plexiform layer (OPL) and inner plexiform layer (IPL). (B–D) Regenerating retinas at 13 (B), 45 (C), and 90 days post-injury (DPI) (D). SV2 staining is visible but disorganized within an emerging OPL and IPL at 13 DPI (B), but displays improved lamination at 45 and particularly at 90 DPI (C,D). ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer; scale bar (in A, applies to all) = 50 μm.

Acknowledgments

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