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Fig. 5
Figure 5. Copb2 heterozygous mice exhibit low bone mass phenotype (A) Micro-CT analysis of spine showed significant decrease in bone architectural parameters in Copb2+/− mice (Het), including the bone volume/total volume (BV/TV, p = 0.014 for males, p = 0.0006 for females) and trabecular thickness (p = 0.007 for males, p < 0.0001 for females). Females also showed decreased trabecular number (p = 0.002). (B) Micro-CT analysis of femurs showed mild reduction in cortical thickness in the females (p = 0.003). Mean values ± SD are indicated for both (A) and (B) (∗p < 0.05, ∗∗p < 0.001).
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Full text @ Am. J. Hum. Genet.