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Fig. 4
Figure 4. Structural integrity of the ER and Golgi apparatus and protein secretion are compromised in copb2b1327/b1327 zebrafish mutants (A–F) Confocal sections of the notochord. Immunolabeling of KDEL in copb2 siblings (A) and copb2b1327/b1327 mutant (B) embryos. Immunolabeling of GM130 in copb2 siblings (C) and copb2b1327/b1327 mutant (D) embryos. Immunolabeling of type II collagen in copb2 siblings (E) and copb2b1327/b1327 mutant (F) embryos (anterior is to the left and dorsal to the top). Images were taken at the level of the yolk extension at 30 hpf.
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Full text @ Am. J. Hum. Genet.