Figure 8

Characterization of three zebrafish orthologues of human catalytic enzymes participating in inflammatory processes mediated by λ-CGN. (A) The abundance of the intra- and extra-cellular superoxide dismutase (SOD) production and its role in zebrafish physiology, 4h post-injection with 3.5% λ-CGN. (A 1-2) Representations of the structural 3-D proteins in zebrafish (blue) plasma overlapping with their predicted Homo sapiens (red) homologous structures. (B) the abundance of the Lysozyme activity following the same setting as for SOD. (B 1) 3-D protein in zebrafish (blue) plasma overlapping with its predicted Homo sapiens (red) homologous structure. The values in the graphs are expressed as relative abundance of the sample average (n = 4). The structural analysis was obtained as described in the methodology.