ZFIN Image: Wareham et al., 2022, FIGURE 2

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Figure Caption

FIGURE 2

Adamts10 MO reduces pou4f1 enhancer-driven GFP fluorescence in zebrafish retinae. Representative fluorescent images of an uninjected (A) and an adamts10 MO-injected (C)Tg(pou4f1-hsp70l:GFP) embryo at 48 hpf showing pou4f1 enhancer-driven GFP fluorescence in the retina (white arrows) and optic nerves (magenta arrows, scale = 100 µm), with corresponding 3D surface plots of fluorescence intensity (B,D). (E) Normalized integrated fluorescence density of uninjected and adamts10 MO-injected embryos at 48 hpf (n = 29 and 23, respectively, ****p < 0.0001, Welch’s t-test). (F) Normalized integrated fluorescence density of uninjected and adamts10 MO-injected embryos at 72 hpf (n = 52 and n = 47, respectively, ****p < 0.0001; Welch’s t-test).

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Acknowledgments

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