ZFIN Image: Bensimon-Brito et al., 2021, Fig. 3

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Fig. 3

MRI analyses of beating hearts reveal increased OFT luminal dilation in alk5a^–/– adult zebrafish. (A, B) Percentage of OFT outer wall (A) and luminal (B) expansion in WT (n = 10) and alk5a^–/– (n = 12) adult zebrafish. Plots show the values for each individual and the mean ± SD; P-values were determined by unpaired t-test (A) or Mann–Whitney test (B). (C–D”) Single frames of MRI cines of WT (C–C”) and alk5a^–/– (D–D”) zebrafish in coronal view. Boxed area is shown in C’, D’ (minimum expansion OFT) and C”, D” (maximum expansion OFT). Magenta dashed line, OFT lumen; yellow dashed line, OFT outer wall. The colour of each dot refers to the same zebrafish across all graphs and images. The dot adjacent to the number symbol (#) identifies the individual zebrafish mentioned in the text. OFT, outflow tract; V, ventricle. Scale bars: 1.5 mm (C, D), 500 µm (C’, C”, D’, D”).

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cardiovasc. Res.