Fig. 3
a Electrophysiological recordings of PTZ treatment showed interictal-like epileptiform discharges (IED) in all genotypes. Representative IEDs show most similarities between TL and panx1b?/? events. b Quantification of IEDs for the first hour of recording for all genotypes revealed that DKO (P?=?1.3?×?10?3, n?=?12) and panx1a?/? (P?=?0.02, n?=?8) had significantly fewer IEDs. No significant difference was found in the amount of IEDs for panx1b?/? larvae compared to TL (P?=?0.34, panx1b?/? n?=?9, TL n?=?7). Data presented as an average number of events per hour?±?s.e.m. N?=?number of larvae. Scale bar: 0.2?mV by 0.5?s. *P?<?0.05, **P?<?0.01, Mann?Whitney U test.