|
Fig. 11
Overview of cognitive and visual performance. For each experiment: 8 wk Full = 8 weeks of hyperglycemia; 8 wk WO = 8-week washout experiment with fish exposed to glucose for 4-weeks followed by a 4-week recovery period; 12 wk Full = 12 weeks of hyperglycemia; 12 wk WO = 12-week washout experiment with fish exposed to glucose for 8-weeks followed by a 4-week recover period. Here we can see that water-treated fish displayed learning in over 50% of the analyses (denoted by the arrow), whereas mannitol displayed learning in exactly 50% of the analyses. Glucose-treated fish displayed learning in 0% of the analyses with two exceptions. At 8 wk washout denoted by the single asterisk, glucose-treated fish showed evidence of slight learning although they did not pass the threshold, and at 12-weeks full denoted by the double asterisk glucose-treated fish showed evidence of memory, but no new learning.