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Fig. 2
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- ZDB-IMAGE-220905-10
- Publication
- Lin et al., 2022 - Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function
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- Figures for Lin et al., 2022
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Fig. 2
Defect in mitosis cell division in Caenorhabditis elegans germline upon WARS-1 depletion. (a) Schematic representation of hermaphrodite germline. (b) DAPI staining of the isolated germline of the control and wars-1 RNAi. The dashed box indicates the mitotically active region of the germline. (c) Zoom-in of the mitotic zone of control and wars-1 RNAi (d) Knocking down wars-1 using RNAi results in a reduction in the number of mitotic cells compared to the control. (n = 6, ****p < .0001). DAPI, 4′,6-diamidino-2-phenylindole; RNAi, RNA interference.
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