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Fig. 2
KDM4C inhibition increased cell apoptosis during oxidative stress in vitro. HEK293 cells treated with the KDM4C inhibitor, JIB04 (1 μM) were used for the study. H2O2 (100 μM) treatment was used to induce oxidative stress. Cell apoptosis was analyzed by flow cytometry at the time points indicated in the figure. The percentages of dead cells at different time points after treatment are shown. Abbreviation: KDM4C, Lysine demethylase 4C.
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