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Figure 6

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ZDB-IMAGE-220816-46
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Figures for Sertori et al., 2022
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Figure Caption

Figure 6

Phenotypic analysis of the L1CAMQ497H knockin mice. (A) Flow cytometric analysis of the frequencies of thymocytes from wildtype (WT) and hemizygous L1cam497H mutant mice. (B) The total and subpopulations of thymic cellularity are shown in bar graphs. The following populations are graphed: DN, CD4-CD8-; DP, CD4+CD8+; CD4+; CD8+; DN1, CD4-CD8-CD25-CD44+; DN2, CD4-CD8-CD25+CD44+; DN3, CD4-CD8-CD44-CD25+; DN4, CD4-CD8-CD44-CD25-. (C) Flow cytometry analysis of splenic CD4+ and CD8+ T cells, B (B220+IgM+) and NK (CD3-CD122+NK1.1+) cells in WT and L1camQ497H mutant mice. (D) The total and subpopulations of splenic cellularity are shown in bar graphs. (E) Flow cytometry analysis of CD44 and CD62L staining of CD4+ and CD8+ T cells. (F) The frequency of CD44+CD62L+ in CD4+ and CD8+ T cells is shown in bar graphs. Data are representative of 2 independent experiments performed. No statistically significant differences were found in any of the indicated populations.

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