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Fig. 8
Effects of different structural procyanidins on dopaminergic neuron injury in the zebrafish PD model. (a) Representative pictures of the dopaminergic neurons in the brains of zebrafish. (b) Quantitative analysis of the tyrosine hydroxylase (TH) density. Control, Blank control group; Model, MPTP (400 μM); Positive control, Deprenyl (40 μM) + MPTP (400 μM); C: C (25 μM) + MPTP (400 μM); EC: EC (25 μM) + MPTP (400 μM); ECG: ECG (25 μM) + MPTP (400 μM); B1: B1 (25 μM) + MPTP (400 μM); B2: B2 (25 μM) + MPTP (400 μM); B3: B3 (25 μM) + MPTP (400 μM); B4: B4 (25 μM) + MPTP (400 μM); B1-G: B1-G (25 μM) + MPTP (400 μM); B2-G: B2-G (25 μM) + MPTP (400 μM); C1: C1 (25 μM) + MPTP (400 μM). Data are expressed as the mean ± SD. All experiments were conducted three times. Different letters (a–e) on the bar represent significant differences, while the same letters represent no significant differences (p < 0.05, one-way ANOVA).