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Fig. 3
Behavioral tests for pharmacological rescue of bdnf−/− zebrafish larvae
(A–C). Normal swimming behavior was rescued by pharmacologic treatments. Distance (A), velocity (B), and rotation (C) was measured for bdnf+/+ larvae, bdnf−/− larvae, bdnf−/− + 7,8-DHF (10 μM).
Mean ± SEM; Kruskal-Wallis ANOVA, Distance moved: K3 = 48.26, p < 0.0001; Velocity: K3 = 77.44, p < 0.0001; Rotation: K3 = 33.05, p < 0.0001; Dunn’s Multiple Comparison test: ∗∗∗p < 0.0001.
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