ZFIN Image: Hu et al., 2022, Fig. 4

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Figure Caption

Fig. 4 Identification of epicardial fibroblasts.

a, Cartoon of lineage tree construction using LINNAEUS. b, Weighted correlations of cell types over the tree were calculated to quantify lineage similarity. c,d, Clustering by lineage correlations at 3 d.p.i. (c) and 7 d.p.i. (d) revealed the epicardial origin of many niche fibroblasts. e, Cre–lox lineage tracing confirmed the epicardial origin of col12a1a-expressing cells. Scale bar, 100 μm. f, Trajectory analysis suggested constitutive fibroblasts as the source of col11a1a and col12a1a fibroblasts at 3 d.p.i.

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