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Fig. 3
Expression of the patient-derived truncated PARD3 (c.1012dupG) variant induced hypoplastic ethmoid plate development in zebrafish. (A) Representative images of the control group and the larvae with patient-derived truncating variant mRNA injection are depicted. Compared with the development of the ethmoid plate in control group larvae, the larvae injected with PARD3-c.1012dupG mRNA showed ethmoid plate dysplasia, with the median ethmoid plate having a certain degree of absence and failing to form a smooth upper edge of the ethmoid plate. Scale bar = 200 μm. (B) Quantification of hypoplastic development of the ethmoid plate between the experimental groups and the control group (bars indicate the means ± SEM. Student’s t test was used to analyse the data. **p < 0.01)
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Full text @ J. Cell. Mol. Med.