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Figure 7

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Publication: Ge et al., 2022 - Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress
All Figures: Figures for Ge et al., 2022

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Figure 7

Details of hormone−related genes detected in the female zebrafish brains by RNA−seq. (A) Clustering analysis of hormone−related genes. (B) Bar plot of pathway enrichment analysis of genes in cluster 1 and cluster 2. False discovery rate (FDR) < 0.05. (C) Protein−protein interaction network of genes in cluster 1 and cluster 2. Nodes represent genes; edges stand for relationship of different genes; different color means different signaling pathways as shown at the bottom. (D) Venn diagram was used to identify down-regulated key genes that were shared in the group of down-regulated genes (a’, b’ and c’) and cluster 1 and 2. (E) Heat map of seven down-regulated key genes, presented as the normalization of TPM (z−score). (F,G) Fold changes and SEM of RNA−seq and qPCR for two representative down-regulated key genes gh1 and lhb.

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