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Fig. 6
Schematic overview of the proposed role of cyclooxygenase-mediated lipid droplet degradation in response to nutrition deprivation in zebrafish hepatocytes. Serum starvation triggers the release of arachidonic acid and augments the production of PGF2α, which is a key molecule promoting lipid mobilization via autophagy/lipophagy and lipolysis as well as mitochondrial energy production.
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