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Fig. 9

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Yu et al., 2022 - A non-polar fraction of Saponaria officinalis L. acted as a TLR4/MD2 complex antagonist and inhibited TLR4/MyD88 signaling in vitro and in vivo
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Fig. 9

fr.1 and saponarin inhibited LPS microinjection-mediated pro-inflammatory cytokines or mediators expression determined by conventional PCR in zebrafish larvae. (A) Relative gene expression of ziNOS, zCOX-2, zTNFα, zIL-6, zIL-1β in LPS-microinjected zebrafish co-treated with fr.1. (B) Relative gene expression of ziNOS, zCOX-2, zTNFα, zIL-6, zIL-1β in LPS-microinjected zebrafish co-treated with saponarin.

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