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Fig. 8
fr.1 and saponarin inhibited LPS microinjection-induced abnormality and mortality in zebrafish larvae. (A) Heartbeat rate of zebrafish larvae after LPS injection (0.5 mg/ml) with fr.1 (0–100 μg/ml) treatment. (B) Classification of phenotypes of zebrafish after LPS injection with fr.1. (C) Critical abnormalities morphologically observed under microscopy after LPS injection in fr.1. (D) Heartbeat rate of zebrafish larvae after LPS injection (0.5 mg/ml) with saponarin (0–100 μg/ml) treatment. (E) Classification of phenotypes of zebrafish after LPS injection with saponarin. (F) Critical abnormalities morphologically observed under microscopy after LPS injection in saponarin. ###p < .001 versus negative control larvae, and ***p < .001 versus LPS treated larvae. (n = 20 in each group).
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