ZFIN Image: Duclaux-Loras et al., 2022, Figure 5

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Figure Caption

Figure 5 UNC45A-deficient organoids recapitulate MVID features.

(A) Bright-field images of control, P1, P4, and UNC45A^KO1 3D organoids. Scale bar: 5000 μm. (B) F-actin staining revealing MVIs in the small subset of P1, P4, and UNC45A^KO 3D organoids that display a central lumen. Scale bar: 20 μm. (C) STED image of F-actin at the apical pole of 2D enterocyte cultures derived from control, P1, P4, and UNC45A^KO1 organoids after a 21-day culture on filters. Scale bars: 1 μm. L, lumen.

Acknowledgments

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