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Publication: Milder et al., 2022 - Neural Activity Correlates With Behavior Effects of Anti-Seizure Drugs Efficacy Using the Zebrafish Pentylenetetrazol Seizure Model
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FIGURE 1

Behavioral profile of zebrafish larvae exposed to PTZ. The following graphs displays the average large count (y-axis) of larvae. (A) The average larval large count is depicted per 15 min interval (x-axis) of the tracking session. Zebrafish larvae were tested PTZ concentrations at 5 mM, 10 mM, 20 mM, and 40 mM (n = 70 fish/solution/concentration). Embryo medium (EM) was used as the control. Significance indicated by *p < 0.05 PTZ vs. EM, two-way ANOVA, Tukey’s post-hoc. (B) The total large count (y-axis) over 90 min is displayed. The respective treatment groups (x-axis). Analyses (one-way ANOVA, Tukey’s post-hoc) are marked * (p < 0.05) to indicate significant differences to embryo medium (EM).

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