Figure 7.
- ID
- ZDB-IMAGE-220430-10
- Publication
- Xue et al., 2022 - Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation
- All Figures
- Figures for Xue et al., 2022
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Figure 7
Figure 7. STAT3i rescued disrupted angiogenesis induced by CSE. (a) Representative images show angiogenic capacities in CSE-exposed HUVECs treated with or without STAT3i (5 µM) at 24 h. (b) Quantification of the blood vessel branch points formed by HUVECs. (c) Representative immunofluorescence images of FN and phalloidin expression in HUVECs with CSE treatment (the arrows indicate FN fibrils). (d) Quantification of the counts of FN fibrils in HUVECs. (e,f) flk::GFP zebrafish embryos were exposed to CSE with or without STAT3i (50 µM) and vasculature formation was observed at 48 h; the blood vessel length was also quantified (n = 20). Data presented are the mean ± s.e.m. Unpaired Student's t-test, #p < 0.0001, **p < 0.01, *p < 0.05.