Image
Figure Caption

Figure 5—figure supplement 3.

Cytosine base editing enables efficient installation of PTCs or missense mutations in two additional cardiac genes.

Summary of C-to-T conversion efficiencies. Sample number used for evoBE4max: n = 5, 6, 6, respectively for (b–d); and BE4-Gam: n = 2 (b). To highlight the dinucleotide context, the nucleotide preceding the target C is shown by red (A), green (T), blue (C) and yellow (G) squares below the respective C.

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