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Publication: Zheng et al., 2022 - Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model
All Figures: Figures for Zheng et al., 2022

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FIGURE 4

Kif15 knocking down leads to abnormal posterior lateral line (PLL) development, which is represented by a decrease in the number of neuromasts (NMs). (A–D) Kif15 inhibition induces the reduction of NMs in zebrafish PLL, while co-injection of Kif15 mRNA with Kif15-MO successfully rescues the decreased number of NMs compared to the Con-MO-treated controls. The PLL NMs are indicated by white arrowheads. Scale bar is 200 μm. (E) Statistical analysis in quantification of PLL NMs in Con-MO-injected controls, Kif15-MO-injected embryos, and Kif15-MO + Kif15 mRNA group (n = 50 in the three groups). Data are recorded as mean ± SEM. *p < 0.05, ****p < 0.0001 vs. Con-MO group; ^####p < 0.0001 vs. Kif15-MO group. (F) Simple and intuitive schematic diagram of changes in PLL development after Kif15 knockdown by MO.

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