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Publication: Lv et al., 2022 - Tcap Deficiency in Zebrafish Leads to ROS Production and Mitophagy, and Idebenone Improves its Phenotypes
All Figures: Figures for Lv et al., 2022

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FIGURE 1

The muscle biopsy specimen from LGMD2G patient. (A) HE staining showed obvious variation in fiber size. (B) MGT staining showed scattered rimmed vacuoles. No ragged red fiber was found in MGT staining. (C–E) The presence of high enzyme activities for NADH (C), COX (D), and SDH (E) staining at the periphery of sarcoplasm and the decreased enzyme activities in the center of sarcoplasm. (F) No blue fibers in SDH-COX double staining. (G) P62 staining showed scattered P62-positive muscle fibers. (H) Increased acid phosphatase enzymatic activity (black arrows). (I) Ultrastructural examination and muscle pathology of patients with LGMD2G.

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