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Fig. 5.

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Publication: Kugler et al., 2022 - Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis
All Figures: Figures for Kugler et al., 2022

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Fig. 5.

Quantification of vascular parameters and cluster analysis. (A) Percentage differences in mean values were quantified for the measured parameters (control MO to MO, and untreated to treated). (B) Cluster analysis identified four main clusters, including (1) inhibitors of anti-angiogenic factors (notch1b MO and Notch inhibition), (2) factors inducing cellular changes (osmotic pressure and membrane rigidity changes), (3) factors with severe angiogenic defects (dll4 MO, actin polymerisation inhibition, tnnt2a MO and jagged1b MO) and (4) inhibitors of angiogenic factors (myosin II inhibition, jagged1a MO, ccbe1 MO and VEGF inhibition).

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