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Figure 6
Figure 6. Mechanism of liver injury caused by 125 nmol/mL Nano-ZnO. (A) Relative levels of ROS; changes in mRNA levels of antioxidant signaling pathways (B) nrf2-a, (C) nrf2-b, (D) gstp1, and (E) nqo1; changes in mRNA levels of ER stress-related genes (F) elf2a and (G) bip. (H) Changes in mRNA levels of the lipid metabolism-related genes acc1, fasn, strebp-1 and strebp-2. (n = 30, * p < 0.05, ** p < 0.01, **** p < 0.0001).
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