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Fig 5

ID: ZDB-IMAGE-220319-54
Publication: Liu et al., 2022 - Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration
All Figures: Figures for Liu et al., 2022

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Figure Caption

Fig 5 Differentially expressed genes between WT and <italic toggle='yes'>nrl</italic>-KO retinas.

(A) The volcano plot shows the 386 differentially expressed genes (196 up-regulated and 190 down-regulated) between WT and nrl-KO retinas at 2 mpf identified via RNA-seq. The red and blue points indicate the up-regulated and down-regulated genes, respectively. (B) The functional categories enriched among the top 100 differentially expressed genes. (C) The expression patterns of rod- and cone-specific phototransduction genes in nrl-KO retinas shown as a heatmap. Most of the rod genes were down-regulated in the nrl-KO retinas.

Acknowledgments

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