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FIGURE 5

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Publication: Stoyek et al., 2022 - Drivers of Sinoatrial Node Automaticity in Zebrafish: Comparison With Mechanisms of Mammalian Pacemaker Function
All Figures: Figures for Stoyek et al., 2022

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FIGURE 5

Effect of mechanical preload on zebrafish and rabbit sinoatrial node automaticity. Representative electrocardiogram (ECG) recording of zebrafish (A) and rabbit (D) sinoatrial node rhythm under unloaded (slack) or mechanically preloaded (5 mg or 300 mg) conditions. Heart rate over time of individual zebrafish (B, n = 8) and rabbit (E, n = 8) sinoatrial nodes when mechanically unloaded or preloaded. Average heart rate and the inter-beat variability of cycle length (measured as the root mean square of its successive differences, RMSSD_CL) of the zebrafish (C) and rabbit (F) sinoatrial node when mechanically unloaded or preloaded. Data shown as mean ± SEM. Means compared by paired, two-tailed, Student’s t-tests; *p < 0.05.

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