IMAGE

Fig. 2.

ID

ZDB-IMAGE-220317-9

Antibodies

Publication

Serrano et al., 2021 - Novel pre-clinical model for CDKL5 Deficiency Disorder

All Figures

Figures for Serrano et al., 2021

Image

Figure Caption

Fig. 2.

Motor function and muscle pathology in cdkl5^−/− fish. (A-C) Quantification of normalized distance travelled (A), speed (B) and time active (C) of cdkl5^+/+, cdkl5^+/− and cdkl5^−/− fish at 6 dpf. Data are mean±s.e.m. for three independent experiments (n=38, 21 and 15 for cdkl5^+/+; n=17, 39 and 19 for cdkl5^+/−; and n=27, 25 and 14 for cdkl5^−/− fish per experiment). *P<0.05; ****P<0.0001; NS, not significant (one-way ANOVA). (D) Maximum intensity projection of a confocal image series of α-myosin and α-Actinin2 antibody staining of cdkl5^+/+ and cdkl5^−/− fish at 2 dpf. (E) Maximum intensity projections of confocal images of α-myosin antibody staining of cdkl5^+/+ and cdkl5^−/− fish at 6 dpf. Scale bars: 100 µm (D); 10 µm (E).

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.