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Figure 7

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Publication: Korte et al., 2022 - Cell Type-Specific Transcriptome Profiling Reveals a Role for Thioredoxin During Tumor Initiation
All Figures: Figures for Korte et al., 2022

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Figure 7

Transformed keratinocyte proliferation is not altered in thioredoxin mutants in the absence of neutrophils. (A) EdU staining (white) of neutrophil-deficient Tg(mpx:Rac2^D57N-mcherry) txn^+/+ and Tg(mpx:Rac2^D57N-mcherry) txn^-/- larvae with KRas^G12V-expressing basal keratinocytes (magenta) 3dpf. (B) Quantification of frequency of EdU-positive KRas^G12V-expressing basal keratinocytes 3dpf in Rac2^D57N txn wt (n=21) and Rac2^D57N txn mutant (n=22) larvae. Scale bar, 10um. Bolded shapes indicate average value per technical replicate, with shaded values representing data points from independent larvae. Samples were analyzed for statistical significance via t-test ns, not significant.

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