ZFIN Image: Banerjee et al., 2022, Figure 3

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Figure Caption

Figure 3

vps11(−/−) mutants show normal distance travelled and velocity at 5dpf and significantly reduced distance travelled and velocity at 7dpf during alternating cycles of light and dark. (A) Representative heat maps of total distance moved by individual vps11(−/−) larvae at 5dpf (mutants = top two rows; siblings = bottom two rows) during a 3-min period of light and dark. (B) Graph representing average distance travelled in 4 alternating light–dark cycles of 3 min each (sibling larvae in blue; mutants in green). (C) Graph representing average distance travelled in light and dark periods. (D) Graph representing average velocity of sibling and vps11(−/−) larvae in light and dark periods. n = 60 siblings and 58 vps11(−/−) larvae. (E) Representative heat maps generated of total distance moved by individual vps11(−/−) larvae at 7dpf (mutants = top two rows; siblings = bottom two rows) in a 3-min period of light and dark. (F) Graph representing average distance travelled in 4 alternating light–dark cycles of 3 min each (sibling larvae in blue; vps11(−/−) mutants in green). (G) Graph representing average distance travelled in light and dark periods. (H) Graph representing average velocity of sibling and vps11(−/−) larvae in light and dark periods. n = 60 siblings and 57 vps11(−/−) larvae. **P < 0.01. Error bars indicate SEM.

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Phenotype details

Acknowledgments

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