ZFIN Image: Aman et al., 2021, Fig. 6

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Figure Caption

Fig. 6 TH regulates densification of the primary hypodermis. (A) Primary hypodermal cells, visualized by imaging ET37:EGFP transgenic fish, have normal density in hypoTH individuals at 6.4 SSL. By 8.2 SSL, the primary hypodermis of hypoTH individuals appeared sparser than euTH controls. (B) Dermal cell density (cell/mm2) was similar in euTH and hypoTH fish at 6.4 SSL. By 8.2 mm SSL, euTH fish had significantly denser dermis than hypoTH siblings. Shared letters above groups indicate means not significantly different in post hoc Tukey Kramer comparisons (TH condition x stage interaction F1,10.4 = 109.1, p < 0.0001; mixed model ANOVA with individuals treated as random effect). Scale bar, (A) 100 μm.

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Acknowledgments

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Reprinted from Developmental Biology, 477, Aman, A.J., Kim, M., Saunders, L.M., Parichy, D.M., Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development, 205-218, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.