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Figure Caption
Fig. 2 EMMA-Mmp2 is proteolytically processed by endogenous Mmp2 activating mechanisms in vivo to yield the expected products. Immunoblot analysis reveals four bands, one that has maintained both C and N-termini (a), two that retain their C-terminus (b, c) and one that only retains its N-terminus (d). Indicated molecular weights are based on conserved cut sites in the pro-peptide (I, II from (Strongin et al., 1993) and III from (Koo et al., 2009)).
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Reprinted from Developmental Biology, 477, Wyatt, R.A., Crawford, B.D., Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail, 155-163, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.