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Figure 6
A possible mechanism for tuning triple-helix stability according to the environmental temperature. When ZF4 cells were cultured below 28 °C, the thermal stability of the procollagen triple helix is almost constant because of the contribution of co-translational modifications. At a higher temperature of 33 °C, the additional mechanism to ensure thermal stability of procollagen triple helix is executed.
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Full text @ Int. J. Mol. Sci.