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Figure 5. Compound 29e showed antivascular activity in vitro. (A) The wound-healing assay was used to evaluate the migration of HUVEC cells, and images were captured at 0 h and 48 h after treatments with 29e. (B) The invasion suppressing effects of 29e against HUVECs cells by Transwell assay. (C) Typical images depicting tubule formation of HUVEC cells by treatments with 29e for 6 h. (D) Quantitative analysis of the migration ability of HUVEC tubule formation.
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Full text @ J Enzyme Inhib Med Chem