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FIGURE 1
Drug-drug interaction using checkerboard assay. Drug interaction was evaluated in MIC50, one-half the MIC50, one-quarter the MIC50, one half of one quarter the MIC50 of CLA (horizontal) in combination with MIC50, one-half the MIC, one-quarter the MIC50, one half of one quarter the MIC50 of OMD (A), AMK (C), and RFB (E). Isobolograms of the resazurin checkerboard synergy testing method showing synergy of CLA with OMD (B). The additive effect observed when CLA interact with AMK (D) and RFB (F). The white line indicates MIC50 value of each compound.
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