FIGURE 6
Linear PcActx peptide alleviated PTZ-induced seizure-related behavior in zebrafish larvae. (A) Representative patterns of behavioral locomotion in zebrafish larvae. The swimming trajectory was recorded every 5 min and is represented by curves. The instantaneous velocity was detected and displayed in different colors (black, <2 mm/s; green, 2–20 mm/s; red, >20 mm/s). (B). Changes in total distance travelled by period. (C). Statistical analysis of total distance travelled. (D). Changes in total distance travelled at high velocity by period (>20 cm/s). (E). Statistical analysis of total distance travelled at high velocity (>20 cm/s). (F). Changes in the duration of high velocity travel by period (>20 cm/s). (G). Statistical analysis of the duration of high velocity travel (>20 cm/s). Data are expressed as means ± SD (n = 9–10). * p < 0.05 vs Ctrl group, ** p < 0.01 vs Ctrl group, # p < 0.05 vs PTZ group, ## p < 0.01 vs PTZ group.