ZFIN Image: Matsumoto et al., 2021, Figure 6

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Figure 6

HIVEP1 knockdown increases systemic inflammation and impairs survival in zebrafish embryos with sepsis. (A) RNA expression of inflammatory cytokines normalized to mobk13 measured by RT-qPCR. Zebrafish embryos (n = 10) were pooled into one biological replicate and five independent experiments were performed. Data shows mean ± SEM (B) The survival rate was significantly lower in the HIVEP1 splice morpholino injected group than that in control (n = 20 per group). Data shows means ± SEM. Experiment performed in triplicate. Survival rates were compared using log-rank statistics. *P < 0.005.

Acknowledgments

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