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Figure 5
PGC-specific overexpression of rab10 leads to PGC mislocalization. (A) rab10-rfp-nos-3′utr mRNA was injected into 8-cell embryos of kop: egfp-UTR-nos3 lines. (B) Representative images of PGCs in embryos injected with rfp-nos mRNA or rab10-rfp-nos-3′utr at prim 5 stage. (C) The number of mislocalized PGCs in each embryo injected with rfp-nos mRNA or rab10-rfp-nos-3′utr at prim 5 stage. (C) The results were representative of more than three independent experiments in triplicate. The average number of mislocalized PGCs were showed in red line by mean ± sd. **** p < 0.0001. Scale bar, 100 µm.
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Full text @ Int. J. Mol. Sci.