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Figure 2
Antiseizure activity based on locomotor analysis of coumarins used in this study. PTZ-induced seizure-like behavior of larvae exposed to vehicle (VHC) only, VHC and pentylenetetrazole (PTZ), positive control valproic acid (VPA) and PTZ, or test compound and PTZ, was expressed as sum of lardist (mm) values during 30 min. Data are shown as the mean ± SEM from three independent experiments, with n = 10 for each experiment (n = 30 in total). Statistical analysis: one-way ANOVA with Dunnett’s multiple comparisons test (GraphPad Prism 5). Significance levels: * p < 0.05; ** p < 0.01; *** p < 0.001.
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Full text @ Int. J. Mol. Sci.